Cholelithiasis refers to the formation of gallstones, which are hard deposits that develop in the gallbladder. While the exact cause is not fully understood, factors such as excess cholesterol, bilirubin, or a dysfunctional gallbladder may contribute to stone formation. The gallbladder stores and releases bile for digestion, but when imbalances occur, gallstones can form, varying in size and number—from multiple small stones to a single large one. For expert cholelithiasis diagnosis and gallbladder stone treatment, consult Dr. Ujwal Zambare, the Best Gallstone Specialist Doctor in Wakad, Pune. Get advanced care for gallbladder stone treatment in Pune today. What Are The Symptoms of Cholelithiasis? You may experience cholecystitis symptoms daily or just once in a while. At times, any of these common symptoms can be severe: Abdominal pain (typically localized to the right upper quadrant of the abdomen) Abdominal swelling, distension or bloating Abdominal tenderness Clay-colored stools Fever and chills Loss of appetite Nausea with or without vomiting Pain that radiates from the abdomen to the right shoulder or back Risk Factors Age over 40 years Crash dieting, or losing weight rapidly (the bile then contains more cholesterol) Diabetes Ethnicity Family history Female gender Liver disease Overweight or obesity What Causes Cholelithiasis? In most cases, cholelithiasis is caused by excessive amounts of cholesterol in the bile that is stored in the gallbladder. The cholesterol hardens to form stone-like substances. Increased body weight and older age are associated with increased levels of cholesterol in the bile. Thus, gallstones are more likely to occur in women, in people who are obese, and in older individuals. Some gallstones develop because the bile contains too much bilirubin, a waste product of the liver that is a component of bile. Gallstones that develop from excess bilirubin are called pigment stones. How is Cholelithiasis Treated? Treatment of cholelithiasis begins with seeking medical care from your health care provider. To determine if you have cholelithiasis, your health care provider may ask you to provide blood samples and undergo diagnostic tests. Some people with cholelithiasis never have any symptoms. If you have symptoms of cholelithiasis, you may be hospitalized and given antibiotics to prevent an infection. Food intake is normally stopped, and intravenous fluids are administered to let the digestive system rest. You may also receive medication for the abdominal pain associated with cholelithiasis. Request A Call Back: Dr. Ujwal Zambare at True Life Clinic & Wellness Center provides best treatment for cholelithiasis, gallbladder stone treatment, and gallbladder disorders in Wakad, Pune. If you’re experiencing symptoms of gallstones or gallbladder issues, don’t wait—consult the best Gastroenterologist in Wakad for an accurate diagnosis and personalized treatment. 📞 For appointments and more information, call: 098159 94279. Book Your Appointment Today

Chronic pancreatitis is a long-term inflammation of the pancreas that does not heal over time. The pancreas, located behind the stomach, plays a vital role in digestion by producing enzymes and regulates blood sugar levels through hormone production. This condition develops when repeated inflammation damages the pancreas, leading to persistent symptoms over months or years. Unlike acute pancreatitis, which occurs suddenly and resolves quickly, chronic pancreatitis can cause ongoing pain, digestive issues, and complications if left untreated. For expert chronic pancreatitis treatment in Wakad, Pune, consult Dr. Ujwal Zambare, the Best Gastroenterologist & Pancreas Specialist. What Causes Chronic Pancreatitis? There are numerous different causes of chronic pancreatitis. The most common cause is long-term alcohol abuse. Approximately 70 percent of cases are linked to alcohol consumption. Autoimmune disease occurs when your body mistakenly attacks your healthy cells and tissues. Inflammatory bowel syndrome, which is inflammation of the digestive tract, and primary biliary cholangitis, which is a chronic liver disease associated with chronic pancreatitis. Autoimmune disease, which occurs when your body mistakenly attacks your healthy cells and tissues A narrow pancreatic duct, which is the tube that carries enzymes from the pancreas to the small intestine A blockage of the pancreatic duct by either gallstones or pancreatic stones Cystic fibrosis, which is a hereditary disease that causes mucus to build up in your lungs Genetics High blood levels of calcium, which is called hypercalcemia Who Is at Risk for Getting Chronic Pancreatitis? Abusing alcohol increases your risk of developing chronic pancreatitis. Smoking is believed to increase the risk of pancreatitis among alcoholics. In some cases, a family history of chronic pancreatitis can increase your risk. Chronic pancreatitis most frequently develops in people between the ages of 30 and 40. The condition is also more common among men than women. What Are the Symptoms of Chronic Pancreatitis? Pain in your upper abdomen Diarrhea Fatty stools, which are loose, pale, and don’t flush away easily Nausea and vomiting Shortness of breath Unexplained weight loss Excessive thirst and fatigue How Is Chronic Pancreatitis Diagnosed? During the early stages of chronic pancreatitis, changes in your pancreas are difficult to see in blood tests. For this reason, blood tests typically aren’t used to diagnose the disease. However, they may be used to determine the amount of pancreatic enzymes in your blood. Blood tests may also be used to check blood cell counts along with kidney and liver function. Your doctor might ask you for a stool sample to test for levels of fat. Fatty stools could be a sign that your body isn’t absorbing nutrients correctly. How Is Chronic Pancreatitis Treated? Treatment for chronic pancreatitis focuses on reducing your pain and improving your digestive function. The damage to your pancreas can’t be undone, but with the proper care, you should be able to manage many of your symptoms. Treatment for pancreatitis can include medication, endoscopic therapies, or surgery. Medications pain medication artificial digestive enzymes if your enzyme levels are too low to digest food normally insulin if you have diabetes steroids if you have autoimmune pancreatitis, which occurs when your body’s immune system attacks your pancreas Endoscopy Some treatments use an endoscope to reduce pain and get rid of blockages. An endoscope is a long, flexible tube that your doctor inserts through your mouth. It allows your doctor to remove pancreatic stones, place small tubes called stents to improve flow, and close leaks.

Acute Pancreatitis Acute pancreatitis is a sudden inflammation of the pancreas, causing severe abdominal pain. While mild cases improve within a few days, severe cases can lead to serious complications. The most common causes include gallstones and excessive alcohol consumption. The pancreas, located behind the stomach, plays a crucial role in digestion by producing enzymes and regulates blood sugar through hormone production, including insulin. Prompt diagnosis and treatment are essential to prevent complications. For expert acute pancreatitis treatment in Wakad, Pune, consult Dr. Ujwal Zambare, the Best Gastroenterologist & Pancreas Specialist. Symptoms of Acute Pancreatitis Tummy (abdominal) pain, just below the ribs, is the usual main symptom. It usually builds up quickly (over a few hours) and may last for several days. The pain can become severe and is typically felt spreading through to the back. The pain may be sudden and intense, or it may begin as a mild pain that is aggravated by eating and slowly grows worse. However, it is occasionally possible to have acute pancreatitis without any pain. This is more common if you have diabetes or have kidney problems. Being sick (vomiting), a high temperature (fever) and generally feeling very unwell are common. Your abdomen may become swollen. If the pancreatitis becomes severe and other organs become involved (for example, your heart, lungs or kidneys) then various other symptoms may develop. You may become lacking in fluid in the body (dehydrated) and have low blood pressure. Complications of Acute Pancreatitis The main complications of acute pancreatitis are Pancreatic pseudocyst – A pancreatic pseudocyst is a collection of fluid containing pancreatic enzymes that forms in and around the pancreas. The pseudocyst goes away spontaneously in some people. In other people, the pseudocyst does not go away and can become infected. Necrotizing pancreatitis – may occur in severe acute pancreatitis. In necrotizing pancreatitis, parts of the pancreas may die and body fluid may escape into the abdominal cavity, which decreases blood volume and results in a large drop in blood pressure, possibly causing shock and organ failure. Severe acute pancreatitis can be life threatening. Infection of the pancreas – Infection of an inflamed pancreas is a risk, particularly in people who have necrotizing pancreatitis. Sometimes, a doctor suspects an infection when a person’s condition worsens and a fever develops, especially if this happens after the person’s first symptoms started to subside. Organ failure – can occur in acute pancreatitis because damage to the pancreas may permit activated enzymes and toxins such as cytokines to enter the bloodstream and cause low blood pressure and damage to other organs such as the lungs and kidneys. This damage can cause some people who have acute pancreatitis to develop failure of other organs, including the kidneys, lungs, or heart, and this failure can lead to death. Causes of Acute Pancreatitis The most common causes (more than 70% of cases) of acute pancreatitis are Gallstones – Gallstones cause about 40% of cases of acute pancreatitis. Gallstones are collections of solid material in the gallbladder . These stones sometimes pass into and block the duct that the gallbladder shares with the pancreas (called the common bile duct). Normally, the pancreas secretes pancreatic fluid through the pancreatic duct into the first part of the small intestine (duodenum). This pancreatic fluid contains digestive enzymes that help digest food. If a gallstone becomes stuck in the sphincter of Oddi (the opening where the pancreatic duct empties into the duodenum), pancreatic fluid stops flowing. Usually, the blockage is temporary and causes limited damage, which is soon repaired. But if the blockage remains, the enzymes collect in the pancreas and begin to digest the cells of the pancreas, causing severe inflammation. Alcohol use – Alcohol use causes about 30% of cases of acute pancreatitis. The risk of developing pancreatitis increases with increasing amounts of alcohol (4 to 7 drinks per day in men and 3 or more drinks per day in women). However, less than 10% of people who frequently consume alcohol develop acute pancreatitis, which suggests additional triggers or other factors are needed for pancreatitis to develop. How alcohol causes pancreatitis is not fully understood. One theory is that alcohol is converted into toxic chemicals in the pancreas that cause damage. Another theory is that alcohol may cause the small ductules in the pancreas that drain into the pancreatic duct to clog, eventually causing acute pancreatitis. Drugs such as angiotensin-converting enzyme (ACE) inhibitors, azathioprine, furosemide, 6-mercaptopurine, pentamidine, sulfa drugs, and valproate Estrogen use in women with high levels of lipids in the blood High levels of calcium in the blood Diagnosis of Acute Pancreatitis